Product Introduction
| 2-METHOXYETHYLAMINE Basic information |
| Product Name: | 2-METHOXYETHYLAMINE |
| Synonyms: | 1-Methoxy-2-aminoethane;RARECHEM AL BW 0200;O-METHYLETHANOLAMINE;2-AMINOETHYL METHYL ETHER;2-METHOXYETHYLAMINE;CAS_109-85-3;2-methoxy-ethanamin;2-Methoxyethanamine |
| CAS: | 109-85-3 |
| MF: | C3H9NO |
| MW: | 75.11 |
| EINECS: | 203-712-1 |
| Product Categories: | Amino Alcohols;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds |
| Mol File: | 109-85-3.mol |
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| 2-METHOXYETHYLAMINE Chemical Properties |
| Melting point | -82 °C |
| Boiling point | 95 °C (lit.) |
| density | 0.864 g/mL at 25 °C (lit.) |
| refractive index | n20/D 1.406(lit.) |
| Fp | 49 °F |
| storage temp. | Store below +30°C. |
| Water Solubility | Completely miscible in water |
| form | clear liquid |
| pka | 9.89(at 10℃) |
| color | Colorless to Almost colorless |
| PH | 12 (100g/l, H2O, 20℃) |
| explosive limit | 3-16.10%(V) |
| BRN | 741854 |
| CAS DataBase Reference | 109-85-3(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanamine, 2-methoxy- (109-85-3) |
| Safety Information |
| Hazard Codes | F,C |
| Risk Statements | 11-34 |
| Safety Statements | 16-26-36/37/39-45 |
| RIDADR | UN 2733 3/PG 2 |
| WGK Germany | 3 |
| RTECS | KR8750000 |
| Autoignition Temperature | 285 °C |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29221990 |
| Toxicity | LD50 orally in Rabbit: 1570 mg/kg |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| 2-METHOXYETHYLAMINE Usage And Synthesis |
| Chemical Properties | clear colorless liquid |
| Uses | 2-Methoxyethylamine is used as a reagent in the preparation of lipid-like materials for delivery of RNAi therapeutics. |
| General Description | Kinetics of reaction of 2-methoxyethylamine with guanosine 5′-phospho-2-methylimidazolide (2-MeImpG) was studied. |
| Purification Methods | An aqueous 70% solution of the amine is dehydrated by azeotropic distillation with *benzene or methylene chloride and the amine is distilled twice from zinc dust. Store it in a tight container as it absorbs CO2 from the atmosphere. [Beilstein 4 IV 1411.] |
| 2-METHOXYETHYLAMINE Preparation Products And Raw materials |
| Raw materials | 2-(2-methoxyethoxy)-1H-Isoindole-1,3(2H)-dione |
| Preparation Products | BIS(2-METHOXYETHYL)AMINE-->2-Benzylidenemalonaldehyde-->1-Piperidinecarboxylic acid, 4-[(2-methoxyethyl)amino]-, phenylmethyl ester-->N,N'-DI(2-METHOXYETHYL)-PERYLENE-TETRACARBONIC ACID, DIAMIDE-->4-Piperidinamine, N-(2-methoxyethyl)-1-(phenylmethyl)--->3-Pyridinecarboxylicacid,2-[(2-methoxyethyl)amino]-(9CI)-->3-(2-Methoxyethyl)-1-phenylthiourea-->1,1,2,2,3,3,4,4,4-Nonafluoro-N-(2-methoxyethyl)-1-butanesulfonamide-->N-(2,4-DICHLOROBENZYL)-2-METHOXYETHANAMINE-->Benzenemethanamine, N-(2-methoxyethyl)-3-nitro--->(2-methoxyethyl)(prop-2-yn-1-yl)amine |
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