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2-Chloro-4'-fluoroacetophenone

2-Chloro-4'-fluoroacetophenone

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Product Introduction

2-Chloro-4'-fluoroacetophenone Basic information
Product Name: 2-Chloro-4'-fluoroacetophenone
Synonyms: .alpha.-Chloro-p-Fluoroacetophenone;AKOS BBS-00004073;ALPHA-CHLORO-4-FLUOROACETOPHENONE;LABOTEST-BB LT00233195;2'-CHLORO-4-FLUOROACETOPHENONE;2-CHLORO-4'-FLUOROACETOPHENONE;2-CHLORO-1-(4-FLUOROPHENYL)ETHANONE;2-Chloro-4'-Fluoroacetophenone 2-Chloro-1-(4-Fluorophenyl)ethanone
CAS: 456-04-2
MF: C8H6ClFO
MW: 172.58
EINECS: 207-256-4
Product Categories: Acetophenone series;(intermediate of fluvastatin);ACETYLHALIDE;456-04-2
Mol File: 456-04-2.mol
2-Chloro-4'-fluoroacetophenone Structure
 
2-Chloro-4'-fluoroacetophenone Chemical Properties
Melting point 47-50 °C(lit.)
Boiling point 247°C
density 1.2752 (estimate)
vapor pressure 1.9Pa at 27.1℃
Fp >230 °F
storage temp. Inert atmosphere,Room Temperature
form Flakes or Platelets
color Light yellow to yellow-beige
Water Solubility Insoluble in water.
Sensitive Lachrymatory
BRN 637860
CAS DataBase Reference 456-04-2(CAS DataBase Reference)
NIST Chemistry Reference «ALPHA»-chloro-para-fluoroacetophenone(456-04-2)
 
Safety Information
Hazard Codes Xi,C,T
Risk Statements 36/37/38-34-23/25-36
Safety Statements 26-28-45-36/37/39-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
RTECS AM6550000
F 9-19
Hazard Note Corrosive/Lachrymatory
HazardClass 8
PackingGroup II
HS Code 29147000
 
MSDS Information
Provider Language
4-Fluorophenacyl chloride English
ACROS English
SigmaAldrich English
ALFA English
 
2-Chloro-4'-fluoroacetophenone Usage And Synthesis
Chemical Properties LIGHT YELLOW TO YELLOW-BEIGE FLAKES OR PLATELETS
Uses 1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole which was synthesized by condensing N-methyl-4-(methylthio)benzamidine with 2-chloro-4?-fluoroacetophenone.
General Description 2-Chloro-4′-fluoroacetophenone on condensation with N-methyl-4-(methylthio)benzamidine yields 1-methyl-2-(4-methylthio)phenyl-4-(4-fluoro)phenylimidazole.
 
2-Chloro-4'-fluoroacetophenone Preparation Products And Raw materials
Preparation Products 1,2-BIS-(4-FLUOROPHENYL)ETHANONE-->3-(4-FLUORO-PHENYL)-1-ISOPROPYL-1H-INDOLE-2-CARBALDEHYDE-->Thiazole, 4-(4-fluorophenyl)-2-phenyl--->F90110-->5-(4-Fluoro-phenyl)-1H-pyrrole-3-carboxylic acid

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