Cremophor EL

Cremophor EL

Product Introduction

Cremophor EL Basic information
Product Name: Cremophor EL
Synonyms: polyoxyethylene castor oil;POLYOXYETHYLENE(10) CASTOR OIL;POLYETHYLENEGLYCOL CASTOR OIL;Castoroil,ethyleneglycolpolymer;Castoroil,ethyleneoxidereactionproduct;Castoroil,polyethoxylated;castoroilpolyoxyethyleneether;polyethoxylatedcastoroil
CAS: 61791-12-6
MF: NULL
MW: 0
EINECS: 500-151-7
Product Categories: Detergents;Detergents A to ZDetergents;Non-Ionic
Mol File: Mol File
Cremophor EL Structure
 
Cremophor EL Chemical Properties
Boiling point 232.6℃[at 101 325 Pa]
density 1.05 g/mL at 20 °C
vapor pressure 0Pa at 25℃
Fp 257℃
storage temp. REFRIGERATOR (+4C)
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka 0[at 20 ℃]
form Viscous Liquid
color Clear yellow
PH 5.0-7.0 (1g/10 mL in H2O)
Odor at 100.00?%. bland
Water Solubility 24.11mg/L at 25℃
Stability: Stable. Incompatible with storng oxidizing agents.
LogP 4.297 at 25℃
CAS DataBase Reference 61791-12-6
EPA Substance Registry System Ethoxylated castor oil (61791-12-6)
 
Safety Information
WGK Germany 1
RTECS GO5661000
HS Code 15153090
 
MSDS Information
Provider Language
SigmaAldrich English
 
Cremophor EL Usage And Synthesis
Chemical Properties light yellow liquid
Uses Polyoxyl 35 Castor Oil is a triglyceride fatty acid which has the potential to repel insects and promote plant growth.
Uses Kolliphor? EL has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.
General Description Kolliphor? EL is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Flammability and Explosibility Not classified
Biochem/physiol Actions Kolliphor? EL is used in lipid-based formulations for drugs and solubilization of cosmetics. Kolliphor EL is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.
 
Cremophor EL Preparation Products And Raw materials
Raw materials Hydrogen peroxide-->Castor oil-->castor oil polyoxyethylene (90) ether
Preparation Products pesticide emulsifier 0203B-->pesticide emulsifier 0206-->Pesticide emulsifier 0207-->Pesticide emulsifier S-118-->pesticide emulsifier 0208-->pesticide emulsifier 0206B-->pesticide emulsifier 0205

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