2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Chemical Properties
Melting point
73-77 °C
Boiling point
445.5±45.0 °C(Predicted)
density
1.17±0.1 g/cm3(Predicted)
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
solubility
Chloroform (Slightly), Methanol (Slightly)
form
Solid
pka
1.85±0.10(Predicted)
color
Pale Beige to Beige
Safety Information
MSDS Information
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Usage And Synthesis
Uses
2-((4-Chloro-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol is an impurity if Erlotinib (E625008) a EGFR-targeted drug in the treatment of non-small cell lung cancer.
Uses
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile is an impurity of Erlotinib (E625008), a EGFR-targeted drug in the treatment of non-small cell lung cancer. EGFR small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival.
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Preparation Products And Raw materials