2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile

Product Introduction

2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Basic information
Product Name: 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile
Synonyms: 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile;Erlotinib Hydrochloride iMpurity 23;2-((4-chloro-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol;Benzonitrile, 2-amino-4,5-bis(2-methoxyethoxy)-;Erlotinib Impurity 134
CAS: 950596-58-4
MF: C13H18N2O4
MW: 266.29
EINECS: 1308068-626-2
Product Categories:  
Mol File: 950596-58-4.mol
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Structure
 
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Chemical Properties
Melting point 73-77 °C
Boiling point 445.5±45.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 1.85±0.10(Predicted)
color Pale Beige to Beige
 
Safety Information
 
MSDS Information
 
 
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Usage And Synthesis
Uses 2-((4-Chloro-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol is an impurity if Erlotinib (E625008) a EGFR-targeted drug in the treatment of non-small cell lung cancer.
Uses 2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile is an impurity of Erlotinib (E625008), a EGFR-targeted drug in the treatment of non-small cell lung cancer. EGFR small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival.
 
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile Preparation Products And Raw materials
Preparation Products Erlotinib

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