Products

1,3,5-Trimethoxybenzene

Product Introduction

1,3,5-Trimethoxybenzene Basic information

Product Name:	1,3,5-Trimethoxybenzene
Synonyms:	1,3,5-Trimethoxybenzene Vetec(TM) reagent grade, 98%;PHLOROGLUCINOL TRIMETHYL ETHER;TRISMETHOXYBENZENE;1,3,5-TriMethoxybenzene ReagentPlus(R), >=99%;1,3,5-Methoxybenzene;1,3,5-TriMetho;1,3,5-trimethoxy-benzen;1,3,5-Trimethyoxybenzene
CAS:	621-23-8
MF:	C9H12O3
MW:	168.19
EINECS:	210-673-4
Product Categories:	Benzene derivates;Aromatic Ethers;ACTIVE PHARMACEUTICAL INGREDIENTS;621-23-8
Mol File:	621-23-8.mol

1,3,5-Trimethoxybenzene Chemical Properties

Melting point	50-53 °C (lit.)
Boiling point	255 °C (lit.)
density	1,126g/cm
refractive index	1,533
Fp	186 °F
storage temp.	Sealed in dry,Room Temperature
solubility	methanol: 0.1 g/mL, clear, colorless
form	Crystalline Powder
color	White to cream
Water Solubility	insoluble
BRN	1307993
InChIKey	LKUDPHPHKOZXCD-UHFFFAOYSA-N
LogP	1.605 (est)
CAS DataBase Reference	621-23-8(CAS DataBase Reference)
NIST Chemistry Reference	1,3,5-Trimethoxybenzene(621-23-8)
EPA Substance Registry System	1,3,5-Trimethoxybenzene (621-23-8)

Safety Information

MSDS Information

1,3,5-Trimethoxybenzene Usage And Synthesis

Chemical Properties	white to cream crystalline powder. Insoluble in water.
Uses	1,3,5-Trimethoxybenzene is a major scent component of the Chinese rose odour. 1,3,5-Trimethoxybenzene is also a useful synthetic intermediate and is used to synthesize triaryl- and triheteroarylmethanes.
Definition	ChEBI: 1,3,5-trimethoxybenzene is a methoxybenzene carrying methoxy groups at positions 1, 3 and 5. It has been found to be a biomarker of flavonoid consumption in humans. It has a role as a biomarker and a human xenobiotic metabolite.
General Description	1,3,5-Trimethoxybenzene effectively cleaves p-methoxybenzyl protecting group on various alcohols and acids. It is the major scent compound present in Chinese rose species.
Solubility in organics	Soluble in Methanol, Ether, Ethanol, Benzene.
Solubility in water	Insoluble
Purification Methods	Sublime it under vacuum. [Beilstein 6 III 635, 6 IV 7362.]

1,3,5-Trimethoxybenzene Preparation Products And Raw materials

Raw materials	3,5-Dibromoanisole-->1-Bromo-3,5-dimethoxybenzene-->Sodium Methoxide-->1,3,5-Tribromobenzene
Preparation Products	P276-->dracorhodin-->2',4',6'-TRIMETHOXYACETOPHENONE-->1,2,3,6-TETRAHYDRO-1-METHYL-4-(2,4,6-TRIMETHOXYPHENYL)-PYRIDINE