Products

2-Chloro-5-chloromethylthiazole

Product Introduction

Description

Product Name:	2-Chloro-5-chloromethylthiazole
Synonyms:	2-CHLORO-5-CHLOROMETHYLTHIAZOLE;2-CHLORO-5-CHLOROMETHYL-1,3-THIAZOLE;2-CHLORO-5-(CHLOROMETHYL)-1,3-THIAZOLE[FOR THIAMETHOXAM];2-CHLORO-5-CHLOROMETHYL THIAZOLE, 98+%;2-chloro-5-(chloromethyl)thiozole;Thiazole, 2-chloro-5-(chloromethyl)- (9CI);2-Chloro-5-(chlormethyl)thiazole;2-Chloro-5-chloromehtylthiazole
CAS:	105827-91-6
MF:	C4H3Cl2NS
MW:	168.04
EINECS:	429-830-5
Product Categories:	Thiazoles;Pesticide intermediate;HALOMETYL;Miscellaneous;API;bc0001;105827-91-6
Mol File:	105827-91-6.mol

2-Chloro-5-chloromethylthiazole Chemical Properties

Melting point	31
Boiling point	268.6±32.0 °C(Predicted)
density	1.503±0.06 g/cm3(Predicted)
refractive index	n20/D1.571
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	soluble in Methanol
pka	0.19±0.10(Predicted)
color	White to Light yellow
BRN	5861439
InChI	InChI=1S/C4H3Cl2NS/c5-1-3-2-7-4(6)8-3/h2H,1H2
InChIKey	VRMUIVKEHJSADG-UHFFFAOYSA-N
SMILES	S1C(CCl)=CN=C1Cl
CAS DataBase Reference	105827-91-6(CAS DataBase Reference)

Safety Information

2-Chloro-5-chloromethylthiazole Usage And Synthesis

Description	2-Chloro-5-chloromethylthiazole is used as pharmaceutical and agrochemical intermediate. It is also used as intermediate of insecticides Thiamethoxam and Clothianidin. It is also useful in in the synthesis of Ritonavir (R535000); a second-generation anti-AIDS drug and a selective HIV protease inhibitor.
Chemical Properties	White crystal or powder
Uses	2-Chloro-5-(chloromethyl)thiazole is a useful synthetic intermediate used in the synthesis of Ritonavir (R535000)

2-Chloro-5-chloromethylthiazole Preparation Products And Raw materials

Raw materials	Chloroform-->Sulfuryl chloride-->2-chloro-3-isothiocyanato-prop-1-ene
Preparation Products	2-[(2-Chloro-thiazol-5-ylMethyl)-aMino]-ethanol-->Thiamethoxam