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| 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE Basic information |
| Product Name: |
1,4-BIS(2-HYDROXYETHYL)PIPERAZINE |
| Synonyms: |
DI(HYDROXYETHYL)PIPERAZINE;AKOS BB-4936;2-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]ETHANOL;1,4'-BIS(2-HYDROXYETHYL)PIPERAZINE;1,4-BIS(2-HYDROXYETHYL)PIPERAZINE;1,4-PIPERAZINEDIETHANOL;1,4-Bis(beta-hydroxyethyl)piperazine;1,4-Di(2-hydroxyethyl)piperazine |
| CAS: |
122-96-3 |
| MF: |
C8H18N2O2 |
| MW: |
174.24 |
| EINECS: |
204-586-0 |
| Product Categories: |
PIPERIDINE |
| Mol File: |
122-96-3.mol |
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| 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE Chemical Properties |
| Melting point |
133.5-136 °C(lit.) |
| Boiling point |
215-220 °C50 mm Hg(lit.) |
| density |
1.097 |
| vapor pressure |
0.004Pa at 20℃ |
| refractive index |
1.4540 (estimate) |
| Fp |
166℃ |
| storage temp. |
Sealed in dry,Room Temperature |
| solubility |
DMSO (Slightly), Methanol (Slightly) |
| form |
powder to crystal |
| pka |
14.66±0.10(Predicted) |
| color |
White to Almost white |
| Water Solubility |
Soluble in water. |
| InChIKey |
VARKIGWTYBUWNT-UHFFFAOYSA-N |
| LogP |
-1.92 at 20℃ |
| CAS DataBase Reference |
122-96-3(CAS DataBase Reference) |
| EPA Substance Registry System |
1,4-Piperazinediethanol (122-96-3) |
| Hazard Codes |
Xi |
| Risk Statements |
36/37/38 |
| Safety Statements |
37/39-26 |
| WGK Germany |
3 |
| RTECS |
TL3675000 |
| TSCA |
Yes |
| HS Code |
2933.59.9500 |
| Provider |
Language |
| SigmaAldrich |
English |
| ACROS |
English |
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| 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE Usage And Synthesis |
| Chemical Properties |
white crystalline powder |
| Uses |
1,4-Piperazinediethanol is useful in the synthesis of salt-inducible kinase inhibitors for the treatment of diseases. |
| Flammability and Explosibility |
Not classified |
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| 1,4-BIS(2-HYDROXYETHYL)PIPERAZINE Preparation Products And Raw materials |
| Raw materials |
Ethanol-->Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Dichloromethane-->Potassium carbonate-->Sodium sulfate-->Piperazine-->2-Chloroethanol-->3-(2-HYDROXYETHYL)-2-OXAZOLIDINONE-->ETHYLENE OXIDE-->2-Bromoethanol-->Carbon dioxide |
| Preparation Products |
1-(2-Hydroxyethyl)piperazine |
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