Products

1-Ethylpiperazine

Product Introduction

1-Ethylpiperazine Basic information

Product Name:	1-Ethylpiperazine
Synonyms:	1-ethyl-piperazin;Piperazine, 1-ethyl-;ETHYLPIPERAZINE-N;LABOTEST-BB LTBB000704;1-ETHYLPIPERAZINE;N-ETHYLPIPERAZINE;NEPRZ;AKOS BBS-00003610
CAS:	5308-25-8
MF:	C6H14N2
MW:	114.19
EINECS:	226-166-6
Product Categories:	Heterocyclic Building Blocks;Piperidines, Piperidones, Piperazines;Piperaizine;Piperazines;Building Blocks;Heterocyclic Building Blocks;Building Blocks;C4 to C8;Chemical Synthesis;bc0001;K00001
Mol File:	5308-25-8.mol

1-Ethylpiperazine Chemical Properties

Melting point	-60 °C
Boiling point	157 °C(lit.)
density	0.899 g/mL at 25 °C(lit.)
vapor pressure	2.48hPa at 20℃
refractive index	n20/D 1.469(lit.)
Fp	110 °F
storage temp.	2-8°C
solubility	soluble
form	Liquid
pka	9.27±0.10(Predicted)
Specific Gravity	0.899
color	Clear colorless to yellow
Water Solubility	soluble
Sensitive	Air Sensitive
BRN	102971
InChIKey	WGCYRFWNGRMRJA-UHFFFAOYSA-N
LogP	-0.1 at 20℃
CAS DataBase Reference	5308-25-8(CAS DataBase Reference)
NIST Chemistry Reference	N-ethylpiperazine(5308-25-8)
EPA Substance Registry System	Piperazine, 1-ethyl- (5308-25-8)

Safety Information

MSDS Information

1-Ethylpiperazine Usage And Synthesis

Chemical Properties	clear colorless to yellow liquid
Uses	1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.
Uses	1-Ethylpiperazine may be used in the preparation of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride.
Synthesis Reference(s)	The Journal of Organic Chemistry, 22, p. 713, 1957 DOI: 10.1021/jo01357a621
Flammability and Explosibility	Flammable

1-Ethylpiperazine Preparation Products And Raw materials

Raw materials	Ethanol-->Sodium hydroxide-->Hydrochloric acid-->Piperazine-->Sodium iodide-->CHLOROETHANE-->1,2-Ethenediylbis(oxy) (9CI)-->1-Piperazinecarboxylic acid, 4-ethyl-, ethyl ester-->1-Piperazinecarboxaldehyde, 4-ethyl--->1,4-DIETHYLPIPERAZINE-->2-Aminoethyl(ethyl)amine
Preparation Products	4-(4-Ethylpiperazin-1-ly)aniline-->Morpholine-->1-ETHYL-4-(4-NITROBENZYL)PIPERAZINE-->1-Piperazineethanamine,4-ethyl-(9CI)