bird - wild,LD50,oral,750mg/kg (750mg/kg),Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
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trans-1-Propenyl-2,4,5-trimethoxybenzene
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alpha-Asarone Usage And Synthesis
Chemical Properties
Asarone is a colorless tryst. M.P. 66-67℃. B.P. 296℃. Pure Asarone is reported to be virtually odorless and tasteless. However, available samples of the material have in experiments shown perceptible influence upon the odor of compositions containing lower boiling perfume materials. Insoluble in water, soluble in alcohol and oils.
Uses
α-Asarone was used in the synthesis of series of α-asarone isomers and were investigated for their hypolipidemic and antiplatelet activities. It is used in the synthesis of anti-inflammatory neolignan. Also used in lignan syntheses for antiallergic agents. It is clinically used as medication for treating epilepsy, cough, bronchitis and asthma. It exhibits neuroprotective, anti-oxidative, anticonvulsive and cognitive enhancing action.
Application
Asarone has been suggested for use as a fixative-blender with Patchouli-like odor character.
Preparation
1) by isolation from the essential oil of Acorus Calamus.
2) synthesis. by reduction of Asaraldehyde.
Definition
ChEBI: The trans-isomer of asarone.
General Description
Asarones are toxic morphogenetic agents. It is also known for its chemosterlant and oviposition stimulant properties. Naturally it can be extracted from Acoruscalamus. α-Asarone is considered as growth inhibitor. This isomer acts as antifeedant with less toxicity.
alpha-Asarone Preparation Products And Raw materials