Alpha-Asarone

Alpha-Asarone

Product Introduction

alpha-Asarone Basic information
Product Name: alpha-Asarone
Synonyms: alpha-Asarion;alpha-Asaron;ASARONE;ASARONE, A-;(e)-1,2,4-trimethoxy-5-(1-propenyl)benzene;A-ASARONE;ALPHA-ASARONE;ALPHA-ASARONE (PHENOL DERIVATIVE)
CAS: 2883-98-9
MF: C12H16O3
MW: 208.25
EINECS: 220-743-6
Product Categories: API;Aromatic Ethers
Mol File: 2883-98-9.mol
alpha-Asarone Structure
 
alpha-Asarone Chemical Properties
Melting point 57-61 °C(lit.)
Boiling point 296 °C(lit.)
density 1.1227 (rough estimate)
refractive index 1.5060 (estimate)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Soluble in chloroform, methanol.
form Solid
color White to Off-White
Sensitive Light Sensitive
λmax 312nm(EtOH)(lit.)
BRN 1910606
LogP 3.406 (est)
CAS DataBase Reference 2883-98-9(CAS DataBase Reference)
NIST Chemistry Reference Asarone(2883-98-9)
 
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 22-24/25
WGK Germany 3
RTECS DC2975000
HS Code 29093090
Hazardous Substances Data 2883-98-9(Hazardous Substances Data)
Toxicity bird - wild,LD50,oral,750mg/kg (750mg/kg),Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
 
MSDS Information
Provider Language
trans-1-Propenyl-2,4,5-trimethoxybenzene English
SigmaAldrich English
 
alpha-Asarone Usage And Synthesis
Chemical Properties Asarone is a colorless tryst. M.P. 66-67℃. B.P. 296℃. Pure Asarone is reported to be virtually odorless and tasteless. However, available samples of the material have in experiments shown perceptible influence upon the odor of compositions containing lower boiling perfume materials. Insoluble in water, soluble in alcohol and oils.
Uses α-Asarone was used in the synthesis of series of α-asarone isomers and were investigated for their hypolipidemic and antiplatelet activities. It is used in the synthesis of anti-inflammatory neolignan. Also used in lignan syntheses for antiallergic agents. It is clinically used as medication for treating epilepsy, cough, bronchitis and asthma. It exhibits neuroprotective, anti-oxidative, anticonvulsive and cognitive enhancing action.
Application Asarone has been suggested for use as a fixative-blender with Patchouli-like odor character.
Preparation 1) by isolation from the essential oil of Acorus Calamus.
2) synthesis. by reduction of Asaraldehyde.
Definition ChEBI: The trans-isomer of asarone.
General Description Asarones are toxic morphogenetic agents. It is also known for its chemosterlant and oviposition stimulant properties. Naturally it can be extracted from Acorus calamus. α-Asarone is considered as growth inhibitor. This isomer acts as antifeedant with less toxicity.
 
alpha-Asarone Preparation Products And Raw materials
Raw materials BETA-ASARONE-->Ethyltriphenylphosphonium bromide-->2,4,5-TRIMETHOXYLPRORIOPHENONE-->2,4,5-Trimethoxybenzaldehyde

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