Building Blocks;C7 to C8;C7 to C8;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Carbonyl Compounds;Ketones
Mol File:
5467-72-1.mol
2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE Chemical Properties
Melting point
285 °C (dec.)(lit.)
storage temp.
Refrigerator
solubility
DMSO (Slightly), Methanol (Slightly)
form
Solid
color
White to Off-White
BRN
3630035
InChIKey
ROAVTVXTYFSQEA-UHFFFAOYSA-N
CAS DataBase Reference
5467-72-1(CAS DataBase Reference)
Safety Information
Hazard Codes
Xi
Risk Statements
36/37/38
Safety Statements
26-36
WGK Germany
3
RTECS
AM5840000
HazardClass
IRRITANT
HS Code
29223900
MSDS Information
Provider
Language
SigmaAldrich
English
ALFA
English
2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE Usage And Synthesis
Uses
2-Amino-4''-bromoacetophenone Hydrochloride is used as a reagent in the synthesis of Ledipasvir (L320100); a potent, once-daily oral NS5A inhibitor used for treatment of hepatitis C virus infection. 2-Amino-4''-bromoacetophenone Hydrochloride is also used in the preparation of the β-receptor agonists (-)-Denopamine (D231485) and (-)-Arbutamine (A766300).
General Description
2-Amino-4′-bromoacetophenone hydrochloride is an organic building block useful for chemical synthesis.
2-AMINO-4'-BROMOACETOPHENONE HYDROCHLORIDE Preparation Products And Raw materials