Alcohols;Building Blocks;C9 to C10;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols
Mol File:
622-08-2.mol
2-Benzyloxyethanol Chemical Properties
Melting point
<-75 °C
Boiling point
265 °C (lit.)
density
1.071 g/mL at 25 °C (lit.)
vapor pressure
7.3hPa at 25℃
refractive index
n20/D 1.521(lit.)
Fp
110 °C
storage temp.
Sealed in dry,Room Temperature
solubility
Chloroform (Slightly), Methanol (Slightly)
pka
14.40±0.10(Predicted)
form
Liquid
color
Clear colorless
Specific Gravity
1.07
Odor
mild rose
Water Solubility
4.282g/L(23 ºC)
BRN
2043566
InChIKey
CUZKCNWZBXLAJX-UHFFFAOYSA-N
LogP
1.01 at 25℃
CAS DataBase Reference
622-08-2(CAS DataBase Reference)
NIST Chemistry Reference
Ethanol, 2-(phenylmethoxy)-(622-08-2)
EPA Substance Registry System
Ethanol, 2-(phenylmethoxy)- (622-08-2)
Safety Information
Hazard Codes
Xn
Risk Statements
22-36/37/38
Safety Statements
26-36-37/39
WGK Germany
3
RTECS
KJ7550000
HS Code
29052900
Hazardous Substances Data
622-08-2(Hazardous Substances Data)
MSDS Information
Provider
Language
Glycol benzyl ether
English
ACROS
English
SigmaAldrich
English
2-Benzyloxyethanol Usage And Synthesis
Description
Benzyl-PEG2-alcohol is a PEG linker with an acid labile, benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Chemical Properties
Ethylene glycol monobenzyl ether is a Colorless to light yellow liquid which will dissolve a large number of organic substances among which are oils, fats, greases, some vinyl resins, dewaxed damar, rosin, ester gum, etc. It is used principally as a high boiling solvent in lacquers, inks, and textile dyeing.
Uses
2-Benzyloxyethanol is used in a base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols.
Uses
2-(Benzyloxy)ethanol has been used in:
9-(2-hydroxyethyl)-linked synthesis of 2,6-diaminopurines
synthesis of benzyloxy ethyl methacrylate monomer by esterification with methacryloyl chloride
a base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 389, 1990 DOI: 10.1016/S0040-4039(00)94562-3
Hazard
Toxic by ingestion.
2-Benzyloxyethanol Preparation Products And Raw materials
