Products

N-Ethyl-p-toluenesulfonamide

Product Introduction

N-Ethyl-p-toluenesulfonamide Basic information

Product Name:	N-Ethyl-p-toluenesulfonamide
Synonyms:	Benzenesulfonamide, N-ethyl-4-methyl-;Ethyl toluenesulfonamide;Ethylp-toluenesulfonamide;n-ethyl-4-methyl-benzenesulfonamid;n-ethyl-4-methylbenzenesulfonamide;N-Ethyl-4-methyl-benzenesulfonamide;N-Ethyltoluene-4-sulfonamide for synthesis;Brinzolamide Impurity 1
CAS:	80-39-7
MF:	C9H13NO2S
MW:	199.27
EINECS:	201-275-1
Product Categories:	Nitrogen Compounds;Organic Building Blocks;Protected Amines
Mol File:	80-39-7.mol

N-Ethyl-p-toluenesulfonamide Chemical Properties

Melting point	63-65 °C(lit.)
Boiling point	208 °C745 mm Hg(lit.)
density	1.26 g/cm3
refractive index	1.5270 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	11.86±0.50(Predicted)
color	White to Off-White
Stability:	Stable. Incompatible with strong oxidizing agents.
LogP	1.960 (est)
CAS DataBase Reference	80-39-7(CAS DataBase Reference)
NIST Chemistry Reference	4-Toluenesulfonamide, n-ethyl-(80-39-7)
EPA Substance Registry System	N-Ethyl-p-toluenesulfonamide (80-39-7)

Safety Information

MSDS Information

Provider	Language
N-Ethyl-p-toluenesulfonamide	English
SigmaAldrich	English

N-Ethyl-p-toluenesulfonamide Usage And Synthesis

Chemical Properties	off-white crystalline solid
Uses	Plasticizer.
Uses	N-Ethyl-4-toluene sulfonamide is a resin carrier in dental materials used for isolating cavities below restorations; plasticizer in polyvinyl alcohollacquers, polyamides, cellulose acetate, etc.
Uses	N-?Ethyl-?p-?toluenesulfonamide is a reagent used in the sulfonamidation of imidazopyridines.
General Description	Platelets (from dilute alcohol or ligroin) or off-white solid.
Air & Water Reactions	Insoluble in water.
Reactivity Profile	An amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Fire Hazard	Flash point data for N-Ethyl-p-toluenesulfonamide are not available; however, N-Ethyl-p-toluenesulfonamide is probably combustible.

N-Ethyl-p-toluenesulfonamide Preparation Products And Raw materials

Raw materials	Ethyl acetate-->Sodium bicarbonate-->Tosyl chloride-->Ethylamine
Preparation Products	Benzenesulfonamide, N-ethyl-2,4-dimethyl--->N-(2,2-Dimethoxyethyl)-4-methylbenzenesulfonamide

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