Products

(R)-(-)-3-Hydroxytetrahydrofuran

Product Introduction

(R)-(-)-3-Hydroxytetrahydrofuran Basic information

Product Name:	(R)-(-)-3-Hydroxytetrahydrofuran
Synonyms:	(R)-(-)-TETRAHYDRO-3-FURANOL;(R)-(-)-3-HYDROXYTETRAHYDROFURAN;(R)-3-HYDROXYTETRAHYDROFURAN;(R)-(-)-3-HYDROXYTETRAHYDROFURANE;3-FURANOL, TETRAHYDRO-, (R);(R)-TETRAHYDROFURAN-3-OL;(3R)-Tetrahydrofuran-3-ol;(3R)-Tetrahydrofuran-3α-ol
CAS:	86087-24-3
MF:	C4H8O2
MW:	88.11
EINECS:	617-796-6
Product Categories:	Furans;Building Blocks for HIV Protease InhibitorsChiral Building Blocks;Alcohols, Hydroxy Esters and Derivatives;Cell Signaling Enzymes;Heterocyclic Building Blocks;HIV Protease Reagents&Envelope Proteins;Chiral Compounds;chiral;Tetrahydrofuran Series;ADVANCED INT.
Mol File:	86087-24-3.mol

(R)-(-)-3-Hydroxytetrahydrofuran Chemical Properties

alpha	-18.5 º (c=2 MeOH)
Boiling point	181 °C (lit.)
density	1.097 g/mL at 25 °C (lit.)
refractive index	n20/D 1.45(lit.)
Fp	180 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform, Methanol (Slightly)
pka	14.49±0.20(Predicted)
form	Liquid
Specific Gravity	1.097
color	Clear colorless
optical activity	[α]20/D 18°, c = 2.4 in methanol
InChI	InChI=1S/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H2/t4-/m1/s1
InChIKey	XDPCNPCKDGQBAN-SCSAIBSYSA-N
SMILES	O1CC[C@@H](O)C1
CAS DataBase Reference	86087-24-3(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

(R)-(-)-3-Hydroxytetrahydrofuran Usage And Synthesis

Chemical Properties	Colorless to light yellow liqui
Uses	(R)-(-)-3-Hydroxytetrahydrofuran is used as a chemical reactant in the synthesis of pharmaceutical agents. Empagliflozin is synthesized using this reactant
Uses	(R)-(-)-3-Hydroxytetrahydrofuran may be used as building block in the synthesis of potent HIV protease inhibitors.

(R)-(-)-3-Hydroxytetrahydrofuran Preparation Products And Raw materials

Raw materials	3-Furanol, tetrahydro-, 3-acetate-->Dihydrofuran-3(2H)-one-->3-Hydroxytetrahydrofuran-->(R)-4-CHLORO-1,3-BUTANEDIOL-->(R)-(+)-1,2,4-BUTANETRIOL-->but-3-en-1-yl 4-methylbenzene-1-sulfonate-->(S)-1,2,4-Butanetriol-->2,3-Dihydrofuran
Preparation Products	Furan, tetrahydro-3-iodo-, (3S)--->(S)-3-P-MESYLOXYTETRAHYDROFURAN