Benzyltrimethylammonium hydroxide Chemical Properties
Melting point
80 °C
Boiling point
65°C
density
1.059 g/mL at 25 °C
vapor pressure
0Pa at 25℃
refractive index
n20/D 1.43
Fp
60 °F
storage temp.
Store below +30°C.
solubility
Miscible with alcohols, hydrocarbons, aromatic hydrocarbons and halogenated solvents.
form
Solution
color
Clear slightly yellow
explosive limit
5.50-36.50%
Water Solubility
Miscible with water, hydrocarbons, aromatic hydrocarbons and halogenated solvents.
Sensitive
Air Sensitive
BRN
3917256
Exposure limits
ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3)
InChIKey
NDKBVBUGCNGSJJ-UHFFFAOYSA-M
LogP
-3 at 20℃
CAS DataBase Reference
100-85-6(CAS DataBase Reference)
EPA Substance Registry System
Benzyltrimethylammonium hydroxide (100-85-6)
Safety Information
Hazard Codes
C,T,F
Risk Statements
34-39/23/24/25-23/24/25-11
Safety Statements
26-36/37/39-45-46-16-28A-7
RIDADR
UN 3267 8/PG 2
WGK Germany
1
RTECS
BO8575000
F
9-23
TSCA
Yes
HazardClass
8
PackingGroup
II
HS Code
29239000
Toxicity
LDLo scu-mus: 35 mg/kg JPETAB 28,367,26
MSDS Information
Provider
Language
Benzyltrimethylammonium hydroxide
English
ACROS
English
SigmaAldrich
English
ALFA
English
Benzyltrimethylammonium hydroxide Usage And Synthesis
Chemical Properties
CLEAR SLIGHTLY YELLOW SOLUTION
Uses
Benzyltrimethylammonium hydroxide is used as a phase-transfer catalyst. It is also used in aldol condensation reactions and base-catalyzed dehydration reactions. Further, it serves as a strong organic base and used in Horner-Wadsworth-Emmons olefination reactions. In addition, it is an active component in the formulation, which is used in silicon wafer cleaning applications.
Uses
Benzyltrimethylammonium hydroxide can be used:
As a base in the synthesis of activated ynesulfonamides and tertiary enesulfonamides.
In the synthesis of 3-indolyl-3-hydroxy oxindoles by treating isatin with indole.
As a precursor for the preparation of quaternary ammonium acetate, benzyltrimethylammonium acetate (NBz111AcO). NBz111AcO solution in DMSO can be used to dissolve cellulose.
Flammability and Explosibility
Not classified
Safety Profile
Poison by subcutaneous route. Astrong base. When heated to decomposition it emits toxicfumes of NH3 and NOx.
Purification Methods
A 38% solution (as supplied) is decolorized (charcoal), then evaporated under reduced pressure to a syrup, with final drying at 75o/1mm pressure. The anhydrous base is obtained by prolonged drying over P2O5 in a vacuum desiccator. [Beilstein 12 IV 2162.]
Benzyltrimethylammonium hydroxide Preparation Products And Raw materials
