Products

(R)-(-)-Benzyl Glycidyl Ether

Product Introduction

(R)-(-)-Benzyl glycidyl ether Basic information

Product Name:	(R)-(-)-Benzyl glycidyl ether
Synonyms:	(R)-(-)-BENZYL GLYCIDYL ETHER;(R)-BENZYL GLYCIDYL ETHER;(R)-BENZYLOXYMETHYL-OXIRANE;RARECHEM AK HZ 0049;(R)-(-)-2-(BENZYLOXYMETHYL)OXIRANE;(R)-(-)-1-BENZYLOXY-2,3-EPOXYPROPANE;(R)-1-BENZYLOXY-2,3-EPOXYPROPANE;(r)-o-benzylglycidol
CAS:	14618-80-5
MF:	C10H12O2
MW:	164.2
EINECS:
Product Categories:	chiral;API intermediates;CHIRAL COMPOUNDS;Chiral Building Blocks;Glycidyl Compounds, etc. (Chiral);Oxiranes;Simple 3-Membered Ring Compounds;Synthetic Organic Chemistry;Chiral Compound
Mol File:	14618-80-5.mol

(R)-(-)-Benzyl glycidyl ether Chemical Properties

Melting point	88-93°C
Boiling point	130 °C (0.1 mmHg)
alpha	-5.4 º (c=5 in toluene)
density	1.077 g/mL at 25 °C(lit.)
refractive index	n20/D 1.517(lit.)
Fp	>230 °F
storage temp.	2-8°C
form	paste (yellow)
Specific Gravity	1.077
color	Colorless to Almost colorless
optical activity	[α]20/D 5.4°, c = 5 in toluene
Water Solubility	Soluble in water.
BRN	3588399
CAS DataBase Reference	14618-80-5(CAS DataBase Reference)

Safety Information

MSDS Information

(R)-(-)-Benzyl glycidyl ether Usage And Synthesis

Chemical Properties	Colorless to light yellow liqui
Uses	Used in the preparation of the lactone fragment of compactin and mevinolin. Chiron in the preparation of syn-1,3-polyols, dideoxynucleosides, and a spiroacetal cyanohydrin.
Synthesis Reference(s)	Tetrahedron Letters, 21, p. 4807, 1980 DOI: 10.1016/0040-4039(80)80145-6
General Description	1H-Pyrazol-3-ylboronic acid hydrate can be used as a reactant in the Suzuki-Miyaura coupling reaction to synthesize pyrazole derivatives by reacting with different aryl halides over the palladium catalyst.
Safety Profile	Mutation data reported. Whenheated to decomposition it emits acrid smoke andirritating vapors.
Purification Methods	This ether in EtOAc is dried (Na2SO4), then purified by flash chromatography using pet ether/EtOAc (5:1) as eluent. The ether distils through a short path distillation apparatus (Kügelrohr) as a colourless liquid. Alternatively, dissolve it in CHCl3, wash it with H2O, dry (Na2SO4), evaporate and purify by silica gel chromatography. [Anisuzzamen & Owen J Chem Soc 1021 1967, Takano et al. Heterocycles 1 6 381 1981, Lipshutz et al. Org Synth 69 82 1990, Takano et al. Synthesis 539 1989, Honda et al. Chem Pharm Bull Jpn 39 1385 1991, Beilstein 12 IV 2277.]

(R)-(-)-Benzyl glycidyl ether Preparation Products And Raw materials

Raw materials	Ethyl acetate-->N,N-Dimethylformamide-->PETROLEUM ETHER-->Sodium hydride-->Benzyl bromide-->(S)-Oxiranemethanol
Preparation Products	(S)-1-(benzylaMino)-3-(benzyloxy)propan-2-ol-->2-Propanol, 1-[(2-broMo-5-fluoro-4-nitrophenyl)aMino]-3-(phenylMethoxy)-, (2R)-

Hot Tags: (r)-(-)-benzyl glycidyl ether, China (r)-(-)-benzyl glycidyl ether manufacturers, suppliers, factory, Reative Monomers, Dodecyl Acrylate, CAS 13048 33 4, 2 2 Ethoxyethoxy Ethylacrylate, Neopentyl Glycol Diacrylate, Isobornyl Acrylate